Research
Macro partitioning
Higher intake of n-3 fatty acids (from fish or plant sources) substantially lowers the risk of cardiovascular mortality.
Include sources of n-3 fatty acids, such as fatty fish or plant sources (like walnuts or flaxseed), in your diet to support heart health and reduce mortality risk.
GoodSupportsHIGH confidence
Prospective cohort studies and secondary prevention trials have provided strong evidence that an increasing intake of n-3 fatty acids from fish or plant sources substantially lowers risk of cardiovascular mortality.
Why this rating
Strong evidence from cohort studies and trials, though specific dosing varies by source (fish vs plant).
Source
Types of Dietary Fat and Risk of Coronary Heart Disease: A Critical Review
Frank B. Hu et al. · Journal of the American College of Nutrition · 2001
DOI 10.1080/07315724.2001.10719008
narrative_reviewCited 903×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- Replacing saturated and trans fats with unsaturated fats (monounsaturated or polyunsaturated) significantly reduces the risk of coronary heart disease, whereas simply reducing total fat intake without regard to fat type does not provide the same benefit.Strong
- Trans fatty acids significantly increase the risk of coronary heart disease by raising LDL cholesterol, lowering HDL cholesterol, increasing lipoprotein(a), and promoting insulin resistance.Strong
Related findings · Macro partitioning
- Total daily protein intake of 1.6 g/kg/day is sufficient for maximizing resistance training-induced muscle gains, with an upper confidence interval of 2.2 g/kg/day.Strong
- Resistance exercise training combined with sufficient dietary protein intake acts synergistically to maximize skeletal muscle hypertrophy, with protein intake saturating around 1.6 g/kg/day for general populations and potentially requiring 2.0-2.2 g/kg/day for resistance-trained individuals.Strong
- Trans fats should be completely eliminated from the diet, as they increase LDL cholesterol, decrease HDL cholesterol, and are directly associated with increased coronary risk.Strong
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