Hormonal
Modest weight loss (5-10%) prevents type 2 diabetes in high-risk individuals, while greater weight loss (>10-15%) can induce remission of established type 2 diabetes, particularly when intervention occurs early in the disease course.
If you have prediabetes or early type 2 diabetes, losing just 5-10% of your body weight can significantly lower your risk of developing full-blown diabetes. If you already have diabetes, losing more weight (10-15%) can potentially put the disease into remission, especially if you act early. Focus on sustainable weight loss through diet, medication, or surgery as advised by your doctor, rather than just managing blood sugar with pills alone.
In clinical trials, modest weight loss (5%–10%) can prevent T2D in high-risk individuals with subclinical disease... In those with established T2D, early weight loss intervention can remit the condition... >10% weight loss may remit T2D
Why this rating
Supported by multiple randomized controlled trials (Diabetes Prevention Study, DiRECT) and meta-analyses.
Source
Obesity as a <scp>multisystem</scp> disease: Trends in obesity rates and <scp>obesity‐related</scp> complications
Shohinee Sarma et al. · Diabetes Obesity and Metabolism · 2021
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