Research

Mixed

Maintaining a Body Mass Index (BMI) between 18.5 and 25.0 kg/m2 reduces the risk of several cancers, including breast (postmenopausal), colon, endometrium, esophagus, gallbladder, pancreas, and kidney cancers.

Strive to maintain a BMI between 18.5 and 25.0 kg/m2 by balancing your caloric intake with physical activity. If you are overweight or obese, focus on gradual weight loss through portion control and increased activity, as this reduces risk for multiple cancers.

GoodSupportsHIGH confidence
Overweight and obesity are associated with increased risk for cancers at several sites: breast (among postmenopausal women), colon, endometrium, adenocarcinoma of the esophagus, gallbladder, pancreas, and kidney... experts consider a BMI within the range of 18.5 to 25.0 kg/m2 to be healthful
T. Byers et al. · CA A Cancer Journal for Clinicians · 2002

Why this rating

Supported by both animal and epidemiological studies, though direct evidence that weight loss reduces cancer risk is not yet convincing.

Source

American Cancer Society Guidelines on Nutrition and Physical Activity for Cancer Prevention: Reducing the Risk of Cancer with Healthy Food Choices and Physical Activity

T. Byers et al. · CA A Cancer Journal for Clinicians · 2002

DOI 10.3322/canjclin.52.2.92

clinical_guidelineCited 335×
Read the paper
DOI resolved against Crossref · corpus check 2026-06-10

This is one finding among thousands. Every one is graded and traced to its source, so you can see what the evidence actually supports. Browse the research →