Research
Hormonal
High-protein diets may be detrimental to glucose control and insulin sensitivity in individuals with diabetes mellitus.
If you have diabetes, be cautious with high-protein diets. They may worsen your blood sugar control and insulin sensitivity. Consult your doctor before significantly increasing protein intake.
ModerateQualifiesMEDIUM confidence
there is some evidence that in diabetics a high-protein diet may be detrimental to glucose control or insulin sensitivity.
Why this rating
Based on specific studies in diabetics showing increased glucose output and decreased sensitivity.
Source
High-protein Weight-loss Diets: Are They Safe and Do They Work? a Review of the Experimental and Epidemiologic Data
Julie Eisenstein et al. · Nutrition Reviews · 2002
DOI 10.1301/00296640260184264
narrative_reviewCited 299×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- High-protein diets do not enhance weight or fat loss compared to lower-protein diets when total energy intake is strictly fixed.Good
- High-protein diets increase satiety and reduce ad libitum energy intake, leading to greater weight and fat loss compared to lower-protein diets when food is consumed freely.Moderate
- High-protein diets (2-3x RDA) increase urinary calcium excretion and may predispose to bone loss, particularly with animal protein sources.Moderate
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