Research
Mixed
Maximal muscle contractions (both shortening and lengthening) significantly increase muscle collagen protein synthesis, likely reflecting remodeling of the myofibrillar basement membrane.
Resistance training strengthens not just muscle fibers but also the connective tissue (collagen) that supports them. This structural remodeling helps the muscle handle higher forces and may reduce injury risk over time.
GoodSupportsHIGH confidence
The increases (P < 0.001) in CPS above rest were identical for both SC and LC and likely represent a remodeling of the myofibrillar basement membrane.
Why this rating
Same study design as N1; robust measurement of collagen synthesis via stable isotopes.
Source
Myofibrillar and collagen protein synthesis in human skeletal muscle in young men after maximal shortening and lengthening contractions
Daniel R. Moore et al. · American Journal of Physiology-Endocrinology and Metabolism · 2004
DOI 10.1152/ajpendo.00387.2004
crossover · n=8Cited 261×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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