Research
Macro partitioning
Mediterranean diets rich in monounsaturated fats (from olive oil and nuts) are more effective at preventing cardiovascular mortality and coronary artery disease than low-fat, low-cholesterol diets.
Adopting a Mediterranean-style diet, which includes healthy monounsaturated fats from olive oil and nuts, is a more effective strategy for preventing heart disease and stroke than following a strict low-fat, low-cholesterol diet.
GoodSupportsHIGH confidence
More recently, trials involving Mediterranean diet (e.g., PREDIMED study) have indicated that healthy monounsaturated fats are more effective in preventing cardiovascular mortality and coronary artery disease than are low-fat, low-cholesterol diets.
Why this rating
Based on the PREDIMED study, a randomized controlled trial, which is higher quality evidence than the observational PURE study.
Source
Cardio-Metabolic Effects of High-Fat Diets and Their Underlying Mechanisms—A Narrative Review
Jibran A. Wali et al. · Nutrients · 2020
DOI 10.3390/nu12051505
narrative_reviewCited 222×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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