Research

Micronutrients & recovery

Selenium may protect against the toxic effects of mercury and reduce cardiovascular risk through antioxidant mechanisms, but current human evidence for selenium supplementation preventing CHD is inconsistent and insufficient to draw firm conclusions.

Do not take selenium supplements specifically for heart disease prevention based on current evidence. Instead, include selenium-rich foods (like fish, eggs, or meat) in your diet, as they may offer protective benefits against mercury and support antioxidant systems, though the exact CVD benefit is not yet proven.

LimitedQualifiesLOW confidence
Selenium protects against mercury toxicity in rats, mice, and quail ... Epidemiologic studies indirectly support a possible protective effect of selenium intake on cardiovascular toxicity of mercury ... an American Heart Association Science Advisory in 1999 concluded that 'little information is available on the preventive effects of [selenium] in human populations'
Dariush Mozaffarian · International Journal of Environmental Research and Public Health · 2009

Why this rating

Animal studies show clear mechanisms, but human observational and trial data are inconsistent, with meta-analyses showing mixed results and no firm conclusions.

Source

Fish, Mercury, Selenium and Cardiovascular Risk: Current Evidence and Unanswered Questions

Dariush Mozaffarian · International Journal of Environmental Research and Public Health · 2009

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