Mixed
Intensive lifestyle interventions in obese individuals with type 2 diabetes produce significant fat mass loss, but this benefit is eroded over 8 years by substantial lean mass loss and fat mass regain, resulting in convergence with non-intervention groups.
If you have type 2 diabetes and are overweight, an intensive lifestyle program can help you lose fat, but be prepared for a long-term challenge. You will likely lose some muscle along with fat, and maintaining the weight loss requires continuous effort. Don't expect the results to stay perfect forever; focus on keeping fat mass down as much as possible, as this reduces long-term health risks.
At 1 year, the intervention group lost fat (5.6 6 0.2 kg) and lean mass (2.3 6 0.1 kg) but regained fat ((cid:3)100%) and lost lean mass between years 1 and 8... Fat mass in the intervention group was lower than that of the comparison group at all post-baseline time points.
Why this rating
Large randomized controlled trial (Look AHEAD) with 8-year follow-up and rigorous DXA measurements.
Source
Changes in body composition over 8 years in a randomized trial of a lifestyle intervention: The look AHEAD study
Henry J. Pownall et al. · Obesity · 2015
DOI 10.1002/oby.21005
Related findings · Mixed
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