Research

Energy balance

Regular aerobic exercise attenuates the metabolic drive to regain weight after long-term weight loss by reducing the energy gap between appetite and expenditure and blunting the shift in fuel utilization that favors rapid weight regain.

If you have lost weight, simply maintaining a lower calorie intake is often not enough to prevent regain because your body biologically fights back by increasing hunger and efficiency. Regular aerobic exercise (like brisk walking or jogging) helps counteract these biological changes by reducing the drive to overeat and improving how your body uses fuel, thereby helping you maintain your new weight more easily.

GoodSupportsHIGH confidence
Regular exercise decreased the rate of regain early in relapse and lowered the defended body weight... Regular exercise reduced the biological drive to eat so that it came closer to matching the suppressed level of energy expenditure... These observations indicate that regimented exercise altered several metabolic adaptations to weight reduction in a manner that would coordinately attenuate the propensity to regain lost weight.
Paul S. MacLean et al. · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · 2009

Why this rating

High-quality rodent model with rigorous metabolic monitoring (indirect calorimetry, body composition), but results are not directly generalizable to humans without further validation.

Source

Regular exercise attenuates the metabolic drive to regain weight after long-term weight loss

Paul S. MacLean et al. · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · 2009

DOI 10.1152/ajpregu.00192.2009

mechanism_only · n=21Cited 81×
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DOI resolved against Crossref · corpus check 2026-06-10

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