Research

Mixed

Obesity is a neurobehavioral disorder resulting from the interaction of a 'vulnerable brain' (biological dysregulation of homeostatic and hedonic pathways) and an obesogenic food environment, rather than solely a failure of willpower.

If you struggle with obesity, understand that it is not just a lack of willpower. Your brain's biological signaling for hunger and satiety, combined with the modern food environment, creates a 'vulnerable brain' state. Effective management requires addressing both the biological signals (e.g., through medical or behavioral interventions) and the environment (e.g., reducing access to hyper-palatable foods).

GoodQualifiesHIGH confidence
Obesity has been described as a neurobehavioral disorder involving the 'vulnerable brain' coexisting within an obesogenic environment.
Patrick J. Stover et al. · Journal of Internal Medicine · 2023

Why this rating

Supported by extensive citations to human and animal studies within the review.

Source

Neurobiology of eating behavior, nutrition, and health

Patrick J. Stover et al. · Journal of Internal Medicine · 2023

DOI 10.1111/joim.13699

narrative_reviewCited 75×
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DOI resolved against Crossref · corpus check 2026-06-10

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