Research
Micronutrients & recovery
Higher achieved plasma phospholipid omega-3 fatty acid levels (from fish oil supplementation) are associated with a significantly lower risk of major perioperative bleeding.
Higher blood levels of omega-3 fatty acids from fish oil are linked to less bleeding during heart surgery. This suggests that ensuring adequate omega-3 status before surgery might be beneficial, though the primary finding is that fish oil itself is safe.
GoodSupportsHIGH confidence
higher levels were associated with lower risk of Bleeding Academic Research Consortium bleeding, with substantially lower risk in the third (odds ratio, 0.30 [95% CI, 0.11–0.78]) and fourth (0.36 [95% CI, 0.15–0.87]) quartiles, compared with the lowest quartile.
Why this rating
Subgroup analysis of biomarkers in a subset of patients (n=564), though still from a high-quality RCT.
Source
Fish Oil and Perioperative Bleeding
Emmanuel Akintoye et al. · Circulation Cardiovascular Quality and Outcomes · 2018
DOI 10.1161/circoutcomes.118.004584
rct · n=1516Cited 68×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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