Adherence
A 10-year intensive lifestyle intervention for weight loss and increased physical activity does not improve overall or domain-specific cognitive function in middle-aged and older adults with type 2 diabetes compared to diabetes support and education.
For adults with type 2 diabetes, a 10-year intensive lifestyle program focused on weight loss and exercise did not improve cognitive function compared to standard diabetes education. While lifestyle changes are crucial for cardiovascular health, they should not be relied upon as a primary strategy to prevent cognitive decline in this specific population based on current evidence.
Assignment to lifestyle intervention was not associated with significantly different overall (P = .10) or domain-specific cognitive function than assignment to diabetes support and education.
Why this rating
Large randomized controlled trial (N=3,751) with long-term follow-up (10-13 years).
Source
Effect of a Long‐Term Intensive Lifestyle Intervention on Cognitive Function: Action for Health in Diabetes Study
Stephen R. Rapp et al. · Journal of the American Geriatrics Society · 2017
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