Research
Energy balance
Lifestyle interventions, including dietary management (DASH/SDR, Low-Energy Diet) and exercise training, improve clinical outcomes in obese HFpEF patients.
Adopt a heart-healthy lifestyle, including a DASH or low-energy diet and regular exercise training. These interventions are the cornerstone of HFpEF management and can reduce hospital readmissions and improve exercise capacity.
GoodSupportsHIGH confidence
Lifestyle intervention, which serves as the cornerstone of weight loss, plays a crucial role in the management of HFpEF. ... The GOURMET-HF trial... demonstrated that the Dietary Approaches to Stop Hypertension (DASH)/sodium-restricted (SDR) diet modestly reduced 30-day hospital readmission rates
Why this rating
Based on multiple clinical trials and guidelines.
Source
Heart failure with preserved ejection fraction and obesity: emerging metabolic therapeutic strategies
Wenwen Zheng et al. · Diabetology & Metabolic Syndrome · 2025
DOI 10.1186/s13098-025-01917-z
narrative_reviewCited 9×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- Sodium glucose cotransporter 2 inhibitors (SGLT2i) significantly reduce the composite risk of cardiovascular death or heart failure hospitalization in patients with heart failure with preserved ejection fraction (HFpEF), regardless of diabetes status.Strong
- Once-weekly semaglutide (2.4 mg) significantly improves health-related quality of life and reduces body weight in obese patients with HFpEF.Good
- Exercise training (ET), including high-intensity interval training (HIIT) and moderate-intensity continuous training, improves functional status, exercise capacity, and quality of life in HFpEF patients.Good
Related findings · Energy balance
- Achieving a total body weight loss of 10-15% (or >10-15 kg) through Total Diet Replacement (TDR) induces remission of Type 2 Diabetes in individuals with short-duration disease.Strong
- Bariatric surgery is superior to medical management alone for inducing significant long-term weight loss, remission of type 2 diabetes, and reduction in mortality for patients with BMI ≥ 40 or ≥ 35 with comorbidities.Strong
- Achieving type 2 diabetes remission requires significant weight loss (≥15 kg) via major caloric restriction, independent of macronutrient composition.Strong
This is one finding among thousands. Every one is graded and traced to its source, so you can see what the evidence actually supports. Browse the research →