Research
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Metabolic surgery, which yields approximately 25% weight loss at 10 years, is associated with a 44% lower risk of invasive cancer compared to non-surgical patients.
For individuals with severe obesity, metabolic surgery can lead to significant weight loss and a substantially lower risk of invasive cancer. Discuss with your doctor if you are a candidate.
GoodSupportsMEDIUM confidence
Metabolic surgery consistently yields ≈25% weight loss at 10 years... Observational studies have reported that patients who undergo metabolic surgery are at a lower risk of developing cancer compared with patients who do not undergo surgery... A meta-analysis of 13 observational studies reported that surgery was associated with a 44% lower risk of invasive cancer (odds ratio: 0.56 [95% CI: 0.46- 0.68]).
Why this rating
Based on a meta-analysis of 13 observational studies, which are subject to bias but show a strong effect.
Source
The Triple Health Threat of Diabetes, Obesity, and Cancer—Epidemiology, Disparities, Mechanisms, and Interventions
Justin C. Brown et al. · Obesity · 2021
DOI 10.1002/oby.23161
narrative_reviewCited 36×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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