Energy balance
Transdermal TRT improves metabolic markers, including resting energy expenditure (REE) and HDL cholesterol, in men with spinal cord injury, potentially reducing cardiovascular disease risk.
Testosterone therapy can help boost your metabolism and improve your 'good' cholesterol (HDL) levels, which is beneficial for heart health. This happens partly because building muscle increases your resting energy expenditure. While this doesn't replace the need for a healthy diet, it provides a metabolic advantage that can help manage weight and cardiovascular risk over time.
Bauman et al., observed a significant increase in resting energy expenditure (pre: 1283 ± 246 kcal/day, 12 months: 1410 ± 250 kcal/day) via favorable changes in LBM with TRT... improvements in LBM and RMR (1393 ± 220 kcal/day) persisted along with elevated HDL-C.
Why this rating
Based on a single study in SCI patients and meta-analyses in able-bodied men; requires replication in larger SCI trials.
Source
Body composition changes with testosterone replacement therapy following spinal cord injury and aging: A mini review
Tom E. Nightingale et al. · Journal of Spinal Cord Medicine · 2017
DOI 10.1080/10790268.2017.1357917
More from this paper
- Transdermal testosterone replacement therapy (TRT) increases lean body mass (LBM) in men with spinal cord injury (SCI) and hypogonadism, with effects comparable to or greater than those seen in able-bodied elderly men.Moderate
- Transdermal TRT has a minimal or inconsistent effect on reducing fat mass (FM) in men with spinal cord injury, unlike its consistent effect on increasing lean body mass.Moderate
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