Research

Adherence

Adherence to dipeptidyl peptidase-4 (DPP4) inhibitor therapy has no significant association with weight change in patients with type 2 diabetes.

If you are prescribed a DPP4 inhibitor for type 2 diabetes, note that adherence does not significantly affect your weight. These medications are weight-neutral, so focus on other aspects of your treatment plan for weight management.

GoodRefutesHIGH confidence
Adherent and poorly adherent DPP4 patients experienced approximately the same amount of weight loss.
Ginger Smith Carls et al. · Obesity Science & Practice · 2017

Why this rating

Large real-world observational study (n=2,272 DPP4) with regression adjustment.

Source

Real-world weight change among patients treated with glucagon-like peptide-1 receptor agonist, dipeptidyl peptidase-4 inhibitor and sulfonylureas for type 2 diabetes and the influence of medication adherence

Ginger Smith Carls et al. · Obesity Science & Practice · 2017

cohort · n=5818Cited 27×
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