Research

Adherence

Intensive lifestyle intervention in type 2 diabetes leads to significant weight loss and improved glycaemic control, but does not reduce cardiovascular morbidity or mortality over 10 years.

Intensive lifestyle changes help you lose weight and lower blood sugar, but they do not guarantee protection against heart attacks or death in type 2 diabetes. You may need additional medications, especially those that protect the heart and help with weight, to fully manage your cardiovascular risk.

GoodQualifiesHIGH confidence
Despite sustained positive effects associated with intensive lifestyle intervention including the need for fewer glucose-lowering drugs and increased likelihood of achieving HbA1c levels <7% (53 mmol/mol) [27], the 10-year follow-up study showed no significant difference between groups for cardiovascular morbidity and mortality [28].
Steve Baín et al. · Diabetes Obesity and Metabolism · 2016

Why this rating

Based on the Look AHEAD study, a major randomized controlled trial with 10-year follow-up.

Source

Management of type 2 diabetes: <scp>t</scp> he current situation and key opportunities to improve care in the <scp>UK</scp>

Steve Baín et al. · Diabetes Obesity and Metabolism · 2016

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