Research

Mixed

In elderly subjects with overweight/obesity and metabolic syndrome, higher baseline abundance of Prevotella 9, Lachnospiraceae UCG-001, and Bacteroides is associated with greater weight loss following a 12-month intensive lifestyle intervention.

If you are older and have metabolic syndrome, your gut bacteria might predict how well you lose weight. Specifically, having more Prevotella 9, Lachnospiraceae UCG-001, and Bacteroides is linked to better results from a Mediterranean diet and exercise plan. While you can't easily change your bacteria overnight, focusing on a fiber-rich Mediterranean diet may help cultivate these beneficial strains over time.

ModerateQualifiesMEDIUM confidence
Differential abundance analysis showed an enrichment of Prevotella 9, Lachnospiraceae UCG-001 and Bacteroides, associated with a higher weight loss after 12-month of follow-up
Alessandro Atzeni et al. · Microorganisms · 2021

Why this rating

Observational analysis within a randomized controlled trial (PREDIMED-Plus); large sample size (n=372), but correlation does not equal causation.

Source

Gut Microbiota Profile and Changes in Body Weight in Elderly Subjects with Overweight/Obesity and Metabolic Syndrome

Alessandro Atzeni et al. · Microorganisms · 2021

DOI 10.3390/microorganisms9020346

cohort · n=372Cited 22×
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DOI resolved against Crossref · corpus check 2026-06-10

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