Mixed
In individuals with overweight or obesity at high risk of type 2 diabetes, a trajectory of weight loss followed by weight regain results in a net loss of fat-free mass (FFM) despite fat mass (FM) returning to baseline levels.
If you are overweight or obese and have experienced a cycle of losing weight and then gaining it back, be aware that your body composition may have worsened even if your weight is back to where it started. Specifically, you may have lost muscle mass (fat-free mass) while regaining fat. To counteract this, prioritize resistance training and adequate protein intake during any future weight loss attempts to preserve muscle, as simply returning to your starting weight does not restore your previous body composition.
These individuals regained FM to baseline levels, but lost 1.50 (0.66, 2.35) kg FFM, adjusted for confounders.
Why this rating
Prospective cohort study with objective BIA measurements and adjustment for multiple confounders, though observational design limits causal inference.
Source
Impact of weight loss and weight gain trajectories on body composition in a population at high risk of type 2 diabetes: A prospective cohort analysis
Thomas Yates et al. · Diabetes Obesity and Metabolism · 2023
DOI 10.1111/dom.15400
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