Mixed
One-anastomosis gastric bypass (OAGB) and Roux-en-Y gastric bypass (RYGB) result in significantly greater reductions in areal bone mineral density (aBMD) at the total hip, femoral neck, and lumbar spine compared to sleeve gastrectomy (SG) within the first year post-surgery.
If you are considering bariatric surgery, know that bypass procedures (OAGB and RYGB) lead to greater bone density loss at the hip and spine than sleeve gastrecty (SG) in the first year. This is likely due to malabsorption of calcium and vitamin D. You should discuss bone health monitoring and supplementation strategies with your surgeon, especially if you choose a bypass procedure.
All surgery types were associated with reductions in aBMD at the total hip, femeral neck, and lumbar spine, which were more pronounced after OAGB and RYGB than after SG (all P < .03), though there was no difference between OAGB and RYGB.
Why this rating
Secondary analysis of a randomized controlled trial (BARI-LIFESTYLE) with a moderate sample size (n=119) and rigorous statistical adjustment for confounders.
Source
One Year Changes in Body Composition and Musculoskeletal Health Following Metabolic/Bariatric Surgery
Friedrich C. Jassil et al. · The Journal of Clinical Endocrinology & Metabolism · 2024
DOI 10.1210/clinem/dgae496
Related findings · Mixed
- Bariatric surgery (VSG and RYGB) is the most effective and sustainable treatment for obesity, producing marked and sustained weight loss that non-surgical interventions cannot match.Strong
- Severely protein-deficient diets (2–3% energy) induce lean body mass loss and metabolic imbalance, whereas adequate protein intake (0.66 g/kg/d minimum) is a prerequisite for maintaining muscle, bone, and physiological function.Strong
- For patients with Class III obesity (BMI >39.9 kg/m2), metabolic bariatric surgery (MBS) is significantly more effective than any currently approved medication, with BilioPancreatic Diversion (BPD) showing the highest estimated weight loss.Strong
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