Mixed
While a protein-polyphenol beverage accelerates early functional adaptations and increases type II fiber hypertrophy, it does not further increase peak isometric torque, overall muscle function, or total quadriceps muscle volume compared to placebo in the later stages of resistance training (sessions 10-30).
Don't expect this specific supplement to make you bigger or stronger than standard protein in the long run. The early boost in function and fiber size is nice, but for overall muscle volume and peak strength after the first month, it offers no advantage over a placebo or standard protein. You can likely stop the specialized polyphenol supplements after the initial adaptation phase.
Similarly, PPB did not further increase peak isometric torque, muscle function, or MyoPS measured posttraining. This suggests that although PPB increases MyoPS and early adaptation, it may not influence longer term adaptations to unilateral RET.
Why this rating
Same high-quality RCT design as N1.
Source
Daily protein-polyphenol ingestion increases daily myofibrillar protein synthesis rates and promotes early muscle functional gains during resistance training
George F. Pavis et al. · American Journal of Physiology-Endocrinology and Metabolism · 2022
DOI 10.1152/ajpendo.00328.2021
Related findings · Mixed
- Bariatric surgery (VSG and RYGB) is the most effective and sustainable treatment for obesity, producing marked and sustained weight loss that non-surgical interventions cannot match.Strong
- Severely protein-deficient diets (2–3% energy) induce lean body mass loss and metabolic imbalance, whereas adequate protein intake (0.66 g/kg/d minimum) is a prerequisite for maintaining muscle, bone, and physiological function.Strong
- For patients with Class III obesity (BMI >39.9 kg/m2), metabolic bariatric surgery (MBS) is significantly more effective than any currently approved medication, with BilioPancreatic Diversion (BPD) showing the highest estimated weight loss.Strong
This is one finding among thousands. Every one is graded and traced to its source, so you can see what the evidence actually supports. Browse the research →