Research
Micronutrients & recovery
Vitamin D3 supplementation (800 IU/day) is the most cost-effective management strategy for sarcopenia in Iran, whereas combination therapies (Protein + Vitamin D3) are not cost-effective despite higher clinical effectiveness.
For managing sarcopenia cost-effectively, Vitamin D3 supplementation (800 IU/day) is the recommended single intervention. While combining it with protein and exercise improves muscle metrics, the added cost makes it economically inefficient for public health systems compared to Vitamin D alone.
ModerateQualifiesMEDIUM confidence
base-case results indicated that vitamin D was the cost-effective strategy... the D strategy was a cost-effective intervention in this evaluation.
Why this rating
It is a cost-utility model based on limited clinical evidence and assumptions (e.g., 90% adherence), not a primary RCT.
Source
Cost-effectiveness analysis of sarcopenia management interventions in Iran
Ali Darvishi et al. · BMC Public Health · 2023
unknownCited 13×
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