Mixed
A 6-month lifestyle-medicine intervention combining a low-carbohydrate diet, resistance/aerobic exercise, and medication withdrawal achieves diabetes remission (A1C <6.5%) in approximately 60-65% of type 2 diabetic patients, regardless of whether they are lean (BMI <25 kg/m2) or obese (BMI ≥25 kg/m2).
If you have Type 2 Diabetes, remission is possible regardless of your weight. A structured 6-month program involving a temporary low-carb/low-calorie diet, regular resistance and aerobic exercise, and the supervised withdrawal of diabetes medications can achieve remission in about 60% of patients. This applies to both lean and obese individuals, suggesting that metabolic health improvements (like lower fasting glucose and visceral fat) are more critical than weight loss alone.
We found that 64.52% of the T2DM subjects in the obese group and 60.64% of T2DM subjects in the lean group achieved diabetes remission [i.e., an A1C level <6.5% (48 mmol/mol)] without any anti-diabetic medications after the 6-month lifestyle-medicine intervention.
Why this rating
Prospective study with a single cohort (n=125) and no control group; results are promising but lack randomization and long-term follow-up data.
Source
Diabetes remission after a lifestyle-medicine intervention on type 2 diabetes in lean and obese Chinese subjects: a prospective study
Wenying Zou et al. · Annals of Palliative Medicine · 2022
DOI 10.21037/apm-22-369
Related findings · Mixed
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