Mixed
Improving alignment with the 2018 WCRF/AICR Cancer Prevention Recommendations (higher score) is associated with a significantly lower risk of developing type 2 diabetes in high-risk adults, particularly in those not taking metformin.
To lower your diabetes risk, aim to improve your overall lifestyle alignment. This means maintaining a healthy weight, being physically active (>=150 min/week), eating more plants/fiber, and limiting fast food, red/processed meat, sugary drinks, and alcohol. Even small improvements in these areas can significantly reduce your risk of developing type 2 diabetes, especially if you are not taking metformin.
For every 1-unit improvement from years 0-1, there was a 31% and 15% lower diabetes risk in ILS (95% CI: 0.56-0.84) and PLB (95% CI: 0.72-0.97) through DPP, and no significant association in MET.
Why this rating
Randomized controlled trial (DPP/DPPOS) with long-term follow-up (15 years), large sample size (N=3,147), and rigorous statistical adjustment.
Source
The 2018 World Cancer Research Fund (WCRF)/American Institute for Cancer Research (AICR) score and diabetes risk in the Diabetes Prevention Program Outcomes Study (DPPOS)
Marissa Shams‐White et al. · BMC Nutrition · 2022
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