Adherence
Systematic health system protocols, including consistent diagnosis and electronic health record decision support, are required to effectively treat early metabolic disease and prevent progression to advanced diabetes and cardiovascular disease.
Health systems should implement protocols to consistently diagnose and treat early metabolic disease. This includes using electronic health records to flag at-risk patients and providing decision support for lifestyle, medication, or surgery referrals. This systematic approach improves outcomes and reduces long-term healthcare costs.
Systematic approaches in health systems must be deployed with clear protocols and supported by streamlined technologies to manage their population’s metabolic health from early through advanced metabolic disease.
Why this rating
Based on observational data and guideline recommendations, though specific RCTs for the protocol itself are not detailed.
Source
A Systematic Approach to Treating Early Metabolic Disease and Prediabetes
Nicholas W. Carris et al. · Diabetes Therapy · 2023
DOI 10.1007/s13300-023-01455-9
More from this paper
- Intensive lifestyle intervention (≥150 min/week moderate exercise and 500-1000 kcal/day caloric deficit) significantly reduces the incidence of new-onset type 2 diabetes compared to placebo, with benefits persisting for at least 21 years.Strong
- Metformin therapy reduces the incidence of new-onset type 2 diabetes in high-risk adults (BMI ≥35, age 25-59, fasting glucose ≥110 mg/dL, or prior gestational diabetes) and provides long-term cardiovascular and microvascular benefits.Strong
Related findings · Adherence
- Regular physical activity (at least 150 minutes/week of moderate-intensity) reduces all-cause and cardiovascular mortality by 20-30% and lowers the risk of type 2 diabetes by 25-35%.Strong
- Increasing physical activity from a sedentary lifestyle to an active one in middle adulthood significantly reduces the risk of coronary events compared to remaining sedentary.Strong
- Resistance exercise is the only intervention capable of consistently restoring muscle function and strength in sarcopenia, partially overcoming age-related anabolic resistance.Strong
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