Mixed
A structured, telehealth-based Individualized Virtual Integrative Medicine (IVIM) protocol combined with semaglutide (branded or compounded) significantly enhances weight loss outcomes, achieving an average 19.5% total body weight reduction at 52 weeks.
If you have obesity and are using semaglutide, sticking to a structured care plan that includes regular medical check-ins, coaching, and app-based tracking can lead to significant weight loss (approx. 20% over a year). This holds true whether you use the branded version or a compounded version, provided you maintain continuous therapy without gaps. The key is adherence and managing side effects through professional support.
Patients with obesity completing 52 weeks of the IVIM clinical protocol on semaglutide lost 19.5 % of total body weight with 47.8 % of patients losing 20 % or more.
Why this rating
Retrospective observational study with self-reported data and significant selection bias (exclusion of non-responders and those with gaps in therapy).
Source
Individualized virtual integrative medicine (IVIM): A clinical model for enhanced GLP-1 therapeutic outcomes
Jessica Duncan et al. · Obesity Pillars · 2025
DOI 10.1016/j.obpill.2025.100188
Related findings · Mixed
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