Macro partitioning
A longitudinal dietary pattern characterized by decreasing low-carbohydrate intake and increasing high-fat intake is associated with a lower risk of all-cause mortality in males, despite being associated with a higher risk of obesity.
For men in this demographic, shifting dietary habits to reduce carbohydrate intake (specifically from a low baseline) while allowing fat intake to increase over time is associated with a lower risk of death, though it comes with a higher risk of obesity. This suggests that for long-term survival, macronutrient quality and trajectory may matter more than total fat avoidance, but weight management remains a challenge.
In the male population, we found that pattern 2 (DLC&IHF&MP) was associated with a lower risk of all-cause mortality... The associations with all-cause mortality (OR = 0.76, 95% CI = 0.60, 0.96) and obesity (OR = 1.24, 95% CI = 1.05, 1.47) were still statistically significant after adjusting for multiple covariates.
Why this rating
Large longitudinal cohort (n=8115), 25-year follow-up, robust statistical modeling (LCTM), but relies on self-reported dietary data and observational design.
Source
Trajectory Patterns of Macronutrient Intake and Their Associations with Obesity, Diabetes, and All-Cause Mortality: A Longitudinal Analysis over 25 Years
Jingxian Huang et al. · Nutrients · 2024
DOI 10.3390/nu16152567
More from this paper
- A longitudinal dietary pattern characterized by decreasing very high-carbohydrate intake and a U-shape protein trajectory is associated with a significantly higher risk of diabetes in males.Good
- A longitudinal dietary pattern characterized by decreasing very high-carbohydrate intake and moderate protein intake is associated with a higher risk of diabetes in females.Good
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