Macro partitioning
A longitudinal dietary pattern characterized by decreasing very high-carbohydrate intake and a U-shape protein trajectory is associated with a significantly higher risk of diabetes in males.
For men, starting with a very high carbohydrate diet, even if you reduce it over time, may increase your risk of developing diabetes, especially if your protein intake follows a U-shaped pattern (high, then lower, then higher). This suggests that managing initial carbohydrate load and protein quality/timing is crucial for diabetes prevention.
We found that a decreasing very high-carbohydrate trajectory together with a U-shape protein trajectory was associated with a higher risk of diabetes in the male population (odds ratio (OR): 2.23; 95% confidence interval (CI): 1.31–3.77).
Why this rating
Longitudinal data, robust statistical modeling, but observational nature and self-reported diagnosis introduce potential bias.
Source
Trajectory Patterns of Macronutrient Intake and Their Associations with Obesity, Diabetes, and All-Cause Mortality: A Longitudinal Analysis over 25 Years
Jingxian Huang et al. · Nutrients · 2024
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