Energy balance
Every 5 kg of weight loss from anti-obesity treatment reduces the risk of myocardial infarction, stroke, and heart failure.
Losing just 5 kg (about 11 lbs) through anti-obesity treatments can significantly lower your risk of heart attack, stroke, and heart failure. This highlights the importance of achieving even modest weight loss for long-term cardiovascular health. Work with your healthcare provider to find a safe and effective weight management strategy.
Guo et al. [9] performed an extensive meta-analysis which revealed that every 5 kg weight loss that resulted from anti-obesity treatment reduced the risk of myocardial infarction, stroke and heart failure compared to the placebo.
Why this rating
Based on an 'extensive meta-analysis' cited in the paper, indicating high-level evidence.
Source
Protein–Ligand Interactions in Cardiometabolic Drug Targets: Focus on Weight Loss and Cardioprotection
Errikos Petsas et al. · Molecules · 2025
DOI 10.3390/molecules30214240
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