Mixed
In oncology patients, muscle-specific strength (MSS) estimated via anthropometry (body weight or calf circumference) or bioimpedance (BIA) provides a reliable alternative to DXA-derived MSS, enabling functional assessment in resource-limited settings.
For cancer patients or clinicians without access to DXA scanners, you can accurately estimate muscle quality by dividing handgrip strength by body weight or calf circumference. This method correlates very strongly with the gold standard DXA test, allowing for effective monitoring of sarcopenia and treatment response in routine clinical settings.
MSS calculated with BIA, body weight, and calf circumference showed very strong correlations with MSS-DXA (r > 0.90)... BIA and anthropometric methods, particularly those using body weight and calf circumference, are reliable and accessible alternatives to DXA for estimating MSS in oncology patients.
Why this rating
Cross-sectional study with a large sample size (n=205) and rigorous statistical correlation analysis against the gold standard.
Source
Assessment of Muscle-Specific Strength in Oncology Patients: Anthropometry as a Reliable Alternative to DXA
Blanca Alabadí et al. · Life · 2025
DOI 10.3390/life15081300
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