Research

Mixed

Adhering to an anti-inflammatory diet (low Dietary Inflammatory Index) does not improve perceived stress or general health outcomes during caloric restriction in healthy, non-obese adults.

If you are restricting calories to lose weight, do not expect that focusing specifically on 'anti-inflammatory' foods will automatically lower your stress levels or improve your general health perception. The CALERIE trial shows that while CR itself may improve general health, the specific inflammatory potential of the diet (DII) does not drive these psychological benefits. Focus on sustainable caloric deficit rather than obsessing over anti-inflammatory metrics for mental health gains.

GoodRefutesHIGH confidence
There was no indication of any contribution of a low DII score on perceived stress and general health in the presence of CR.
Rachel Silver et al. · Current Developments in Nutrition · 2020

Why this rating

Secondary analysis of a randomized controlled trial (CALERIE) with a large sample size (n=218) and rigorous statistical adjustment.

Source

No Effect of the Dietary Inflammatory Index on Psychological Health During Caloric Restriction: A Secondary Analysis of the CALERIE Trial Data

Rachel Silver et al. · Current Developments in Nutrition · 2020

DOI 10.1093/cdn/nzaa046_067

rct · n=218
Read the paper
DOI resolved against Crossref · corpus check 2026-06-10

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