Research
Micronutrients & recovery
Incretin-based therapies may attenuate intestinal iron absorption, independent of reduced intake, potentially contributing to iron deficiency in susceptible individuals.
Monitor iron levels if you have a history of anemia or low iron, as semaglutide may slightly reduce absorption.
LimitedSupportsLOW confidence
A pilot study assessing intestinal iron absorption using an oral iron absorption test before and after initiation of semaglutide demonstrated attenuated intestinal iron absorption, with a median reduction of 13% after 10 weeks of treatment [33].
Why this rating
Based on a small pilot study (N=?? implied small) with short duration.
Source
Micronutrient Deficiencies in the Era of Second-Generation Incretin-Based Therapies for Obesity
Andrijana Koceva et al. · Nutrients · 2026
narrative_review
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