Research

Mixed

Combined aerobic and resistance exercise provides additive or synergistic benefits for MASLD by simultaneously enhancing oxidative metabolism and increasing skeletal muscle mass.

For the best results, combine aerobic exercise (like brisk walking or cycling) with resistance training (like weight lifting). Aim for 150-300 minutes of moderate aerobic activity and 2-3 resistance sessions per week. This combination targets both your liver's fat processing and your muscle's ability to use energy, providing a comprehensive metabolic benefit.

ModerateSupportsMEDIUM confidence
Importantly, emerging evidence suggests that combined aerobic and resistance exercise may provide additive or synergistic benefits. By simultaneously enhancing oxidative metabolism and increasing skeletal muscle mass, combined training may improve whole-body substrate utilization and reduce excess substrate delivery to the liver [81].
Hee‐Tae Roh et al. · Medicina · 2026

Why this rating

The paper cites evidence but notes that comparative studies have generally failed to demonstrate clear superiority of one modality over the other, though combined is suggested.

Source

Exercise as a Metabolic Therapy for MASLD: Beyond Weight Loss Toward Sustainable Exercise Strategies

Hee‐Tae Roh et al. · Medicina · 2026

DOI 10.3390/medicina62040784

narrative_review
Read the paper
DOI resolved against Crossref · corpus check 2026-06-10

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