Adherence
Continuous Positive Airway Pressure (CPAP) is the recommended first-line treatment for stable ambulatory patients with OHS who also have severe Obstructive Sleep Apnea (OSA).
If you have OHS and severe sleep apnea, CPAP is the standard first treatment. You need to use it every night. While it can be uncomfortable at first, it is necessary to keep your airways open and manage your breathing until weight loss interventions can potentially resolve the underlying syndrome.
For stable ambulatory patients diagnosed with OHS and concomitant severe OSA (apnea–hypopnea index > 30 events/h), we suggest initiating first-line treatment with CPAP therapy rather than NIV
Why this rating
The guideline states 'very low level of certainty in the evidence'.
Source
Evaluation and Management of Obesity Hypoventilation Syndrome. An Official American Thoracic Society Clinical Practice Guideline
Babak Mokhlesi et al. · American Journal of Respiratory and Critical Care Medicine · 2019
DOI 10.1164/rccm.201905-1071st
More from this paper
- Obese adults with obesity hypoventilation syndrome (OHS) should undergo weight-loss interventions targeting a sustained loss of 25-30% of body weight to achieve resolution of the syndrome, with bariatric surgery being the most effective method for achieving this threshold.Weak
- Serum bicarbonate levels below 27 mmol/L can effectively rule out Obesity Hypoventilation Syndrome (OHS) in obese patients with sleep-disordered breathing who have a low to moderate pretest probability (<20%) of having the condition.Weak
Related findings · Adherence
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