Micronutrients & recovery
Serum bicarbonate levels below 27 mmol/L can effectively rule out Obesity Hypoventilation Syndrome (OHS) in obese patients with sleep-disordered breathing who have a low to moderate pretest probability (<20%) of having the condition.
If you are obese and have sleep apnea, your doctor can check your blood bicarbonate level. If it is below 27, it is very unlikely you have the serious breathing condition called OHS, and you might not need more invasive blood tests. If it is higher, you likely need further testing.
We suggest that clinicians use a serum bicarbonate level <27 mmol/L to exclude the diagnosis of OHS in obese patients with sleep-disordered breathing when suspicion for OHS is not very high (<20%)
Why this rating
Guideline states 'very low level of certainty in the evidence'.
Source
Evaluation and Management of Obesity Hypoventilation Syndrome. An Official American Thoracic Society Clinical Practice Guideline
Babak Mokhlesi et al. · American Journal of Respiratory and Critical Care Medicine · 2019
DOI 10.1164/rccm.201905-1071st
More from this paper
- Obese adults with obesity hypoventilation syndrome (OHS) should undergo weight-loss interventions targeting a sustained loss of 25-30% of body weight to achieve resolution of the syndrome, with bariatric surgery being the most effective method for achieving this threshold.Weak
- Continuous Positive Airway Pressure (CPAP) is the recommended first-line treatment for stable ambulatory patients with OHS who also have severe Obstructive Sleep Apnea (OSA).Weak
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