Research

Adherence

Bupropion and varenicline are effective interventions for reducing tobacco smoking in persons with serious mental illness, with high-strength evidence.

If you have a serious mental illness and smoke, using bupropion or varenicline is a highly effective, evidence-based strategy to quit. This directly addresses a major health-risk behavior that contributes to premature mortality in this population.

StrongSupportsHIGH confidence
The strength of the evidence was high for 2 interventions: the best available evidence suggested that bupropion had beneficial effects on point and continuous abstinence from tobacco smoking... and that varenicline had beneficial effects on both point and continuous abstinence.
Emma E. McGinty et al. · Schizophrenia Bulletin · 2015

Why this rating

Rated 'high' strength of evidence by the authors.

Source

Interventions to Address Medical Conditions and Health-Risk Behaviors Among Persons With Serious Mental Illness: A Comprehensive Review

Emma E. McGinty et al. · Schizophrenia Bulletin · 2015

systematic_reviewCited 135×
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