Hormonal
Pima Indian males exhibit significantly lower beta-adrenergic sensitivity (higher chronotropic dose-25) compared to Caucasian males, independent of body fat levels.
This research highlights that Pima Indian men may have a biological baseline of lower heart rate responsiveness to beta-adrenergic stimulation compared to Caucasian men, regardless of weight. This is a physiological trait, not a lifestyle failure. It may contribute to lower hypertension rates but higher obesity prevalence in this population. Focus on overall health metrics rather than trying to force a 'Caucasian' physiological response.
After adjustment for percent body fat, b-adrenergic sensitivity was still significantly lower in Pima than in Caucasian males (CD25 = 3.44 +/- 2.24 vs. 2.57 +/- 1.60 mg, P = 0.05).
Why this rating
Randomized controlled physiological study with matched controls, though sample size is moderate (n=87).
Source
Pima Indian Males Have Lower β-Adrenergic Sensitivity Than Caucasian Males
P. Antonio Tataranni et al. · The Journal of Clinical Endocrinology & Metabolism · 1998
DOI 10.1210/jcem.83.4.4687
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