Research
Hormonal
In males, increased adiposity is associated with decreased beta-adrenergic sensitivity, whereas this correlation is absent in females.
For men, carrying more body fat tends to blunt the heart's responsiveness to adrenaline-like signals. This link is not seen in women in this study. This suggests that weight management strategies might need to consider sex-specific physiological responses to adiposity.
GoodQualifiesHIGH confidence
In conclusion, our data suggest that increased adiposity is accompanied by decreased b-adrenergic sensitivity in males only.
Why this rating
Consistent with prior literature cited and supported by regression analysis in the study.
Source
Pima Indian Males Have Lower β-Adrenergic Sensitivity Than Caucasian Males
P. Antonio Tataranni et al. · The Journal of Clinical Endocrinology & Metabolism · 1998
DOI 10.1210/jcem.83.4.4687
cross_sectional · n=87Cited 20×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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