Mixed
An intensive lifestyle intervention (ILI) may exacerbate the severity of self-reported problem-solving complaints in Type 2 Diabetes patients who have pre-existing cognitive complaints and a history of cardiovascular disease.
If you have Type 2 Diabetes, existing cognitive complaints, and a history of heart disease, be aware that aggressive lifestyle interventions might be associated with increased reports of problem-solving difficulties. Discuss this specific risk with your doctor to determine if a modified or less intensive approach is safer for your cognitive health.
ILI may have exacerbated the severity of complaints about problem-solving ability during follow-up among individuals with baseline complaints and cardiovascular disease (OR=2.949 [1.378,6.311]).
Why this rating
Large RCT, but the outcome is self-reported severity and the subgroup is small (N=94 for CVD+complaints), making it exploratory but statistically significant.
Source
Impact of a Multidomain Intensive Lifestyle Intervention on Complaints About Memory, Problem-Solving, and Decision-Making Abilities: The Action for Health in Diabetes Randomized Controlled Clinical Trial
Mark A. Espeland et al. · The Journals of Gerontology Series A · 2018
DOI 10.1093/gerona/gly124
Related findings · Mixed
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