Energy balance
A long-term intensive lifestyle intervention (caloric restriction and increased physical activity) does not significantly reduce the prevalence of electrocardiographic left ventricular hypertrophy (ECG-LVH) in overweight or obese adults with type 2 diabetes.
For individuals with type 2 diabetes and obesity, engaging in a long-term intensive lifestyle intervention (diet and exercise) is unlikely to reverse electrocardiographic signs of left ventricular hypertrophy, even if it helps maintain weight loss. While lifestyle changes are crucial for overall health, patients should not expect this specific cardiac structural improvement as a guaranteed outcome of modest weight loss.
The Look AHEAD long-term lifestyle intervention does not significantly lower ECG-LVH in overweight and obese adults with type 2 diabetes.
Why this rating
Large-scale, multicenter, randomized clinical trial (Look AHEAD) with long-term follow-up (median 9.5 years) and rigorous statistical analysis.
Source
Long-Term Effects of an Intensive Lifestyle Intervention on Electrocardiographic Criteria for Left Ventricular Hypertrophy: The Look AHEAD Trial
Tina E. Brinkley et al. · American Journal of Hypertension · 2018
DOI 10.1093/ajh/hpy004
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