Mixed
Higher BMI categories (Class I-III obesity) are associated with adverse cardiometabolic profiles, including lower HDL-C, higher triglycerides, higher hsCRP, higher prevalence of hypertension and diabetes, lower physical activity (step counts), and higher mental health distress (PHQ-9/GAD-7 scores) compared to normal weight.
Maintaining a healthy weight is crucial for reducing cardiometabolic risk, but it is not the only factor. Individuals, especially those who are underweight or have obesity, should monitor blood pressure, lipids, inflammation (hsCRP), and mental health. Regular physical activity and managing stress are key components of overall health regardless of BMI category.
The obesity categories had higher proportions of participants with CAC scores >0, hypertension, diabetes, lower HDL-C, lower vitamin D, higher triglycerides, higher hsCRP, lower mean step counts, higher mean PHQ-9 scores, and higher mean GAD-7 scores.
Why this rating
Large sample size (n=2493), multi-ethnic, deeply phenotyped, but cross-sectional design limits causal inference.
Source
Relationship between body mass index and cardiometabolic health in a multi-ethnic population: A project baseline health study
Nishant Shah et al. · American Journal of Preventive Cardiology · 2024
DOI 10.1016/j.ajpc.2024.100646
Related findings · Mixed
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