Research
Mixed
Intensive lifestyle intervention improves cardiovascular risk factors including fitness, HbA1c, systolic blood pressure, and HDL-C levels in individuals with type 2 diabetes, but does not significantly improve LDL-C levels compared to usual care when medication use is accounted for.
While lifestyle changes improve many heart health markers, they may not lower LDL cholesterol as effectively as medications for some individuals. It is important to discuss lipid management with a healthcare provider, as medication might be necessary to achieve LDL goals.
StrongQualifiesHIGH confidence
Averaged across 4 years, ILI produced greater weight losses, increases in fitness, and greater improvements in all CVD risk factors, except LDL-C level, compared with the control group.
Why this rating
Large RCT with detailed lipid profiling and medication adjustment data.
Source
Long-term Effects of a Lifestyle Intervention on Weight and Cardiovascular Risk Factors in Individuals With Type 2 Diabetes Mellitus
Rena R Wing · Archives of Internal Medicine · 2010
rct · n=5145Cited 1,170×
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