Research

Macro partitioning

High-protein diets, particularly those with a high Glycemic Index, can increase LDL cholesterol levels, negating cardiovascular benefits despite potential fat loss.

Be cautious with high-protein diets that also rely on high-GI carbohydrates (like white rice/pasta with meat). This combination may raise your LDL cholesterol. Opt for high-protein diets paired with low-GI carbohydrates to avoid this risk.

GoodRefutesHIGH confidence
Mean ± SE low-density-lipoprotein cholesterol levels declined significantly in the diet 2 group... but increased in the diet 3 group
Joanna McMillan-Price et al. · Archives of Internal Medicine · 2006

Why this rating

RCT with clear biochemical markers.

Source

Comparison of 4 Diets of Varying Glycemic Load on Weight Loss and Cardiovascular Risk Reduction in Overweight and Obese Young Adults

Joanna McMillan-Price et al. · Archives of Internal Medicine · 2006

rct · n=129Cited 331×
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