Mixed

Rapid weight loss via a low-energy diet (810 kcal/day for 8 weeks) induces gender-specific metabolic adaptations: men lose more total body weight and fat mass with greater improvements in metabolic syndrome Z-score, whereas women lose relatively more fat-free mass and experience larger reductions in HDL cholesterol and hip circumference, despite similar improvements in insulin resistance.

If you are using a very low-calorie diet (around 800 kcal/day) to jumpstart weight loss, expect different results based on your sex. Men will likely lose more total weight and fat, with better improvements in overall metabolic risk. Women may lose less total weight but will still improve insulin resistance. However, women should be aware that this specific rapid loss phase may lead to greater loss of lean muscle and a drop in 'good' cholesterol (HDL). This doesn't mean the diet is 'bad' for women, but it highlights the need for careful monitoring and a strong focus on preserving muscle mass (via protein and resistance training) once you transition to a maintenance diet.