Research
Energy balance
n-3 PUFA supplementation during caloric restriction increases ketogenesis (beta-hydroxybutyrate levels) and reduces lipogenesis (palmitoleic acid levels), indicating enhanced fatty acid oxidation.
n-3 PUFAs may help your body burn fat more efficiently during a diet by increasing ketone production and reducing the creation of new fat.
ModerateSupportsMEDIUM confidence
Significantly higher increase in beta-hydroxybutyrate was found in the n-3 group showing higher ketogenesis and possible higher fatty acid oxidation. A significant decrease of palmitoleic acid (16:1n-7) and vaccenic acid (18:1n-7) in triglycerides probably reflected lower lipogenesis.
Why this rating
Small sample size, but biochemical markers are clearly reported.
Source
The influence of n-3 polyunsaturated fatty acids and very low calorie diet (VLCD) during a short-term weight reducing regimen on weight loss and serum fatty acid composition in severely obese women
M Kunešová et al. · Physiological Research · 2006
DOI 10.33549/physiolres.930770
rct · n=20Cited 149×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- Supplementing a very low calorie diet (VLCD) with long-chain n-3 polyunsaturated fatty acids (n-3 PUFA) significantly enhances weight loss and BMI reduction in severely obese women compared to VLCD alone.Moderate
- Increased serum levels of Docosahexaenoic acid (DHA) are significantly correlated with greater BMI loss during n-3 PUFA supplementation.Moderate
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