Research

Energy balance

Modified alternate-day fasting (ADF) significantly reduces body weight, BMI, waist circumference, and blood pressure in overweight/obese women over a 6-week period.

Try a modified alternate-day fasting schedule for 6 weeks. Eat very little (about 25-30% of your needs) on 3 specific days (e.g., Sat, Mon, Wed) and eat normally (around 1700-1800 kcal) on the other 3 days. This approach significantly reduces weight and blood pressure in obese women, potentially offering a more flexible alternative to daily dieting.

ModerateSupportsMEDIUM confidence
During the course of the trial, BW of the subjects decreased (p < 0/0001) from 84/3 ± 11/44 kg to 78/3 ± 10/18 kg. Waist Circumference decreased from 87/87 ± 9/74 to 82/86 ± 9/68(p < 0/001). Reduction in systolic BP was seen from 114.8 ± 9.16 to 105.13 ± 10.19 mmHg (p < 0/001) and diastolic BP changed from 82.86 ± 10.6 to 74.5 ± 10.8 (P < 0.05).
Samira Eshghinia et al. · Journal of Diabetes & Metabolic Disorders · 2013

Why this rating

Small sample size (n=15), no control group, short duration (6 weeks), but statistically significant results for primary metrics.

Source

The effects of modified alternate-day fasting diet on weight loss and CAD risk factors in overweight and obese women

Samira Eshghinia et al. · Journal of Diabetes & Metabolic Disorders · 2013

DOI 10.1186/2251-6581-12-4

clinical_trial · n=15Cited 142×
Read the paper
DOI resolved against Crossref · corpus check 2026-06-10

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