Mixed

A combined weight loss intervention using meal replacements and guided aerobic exercise produces comparable total weight loss in pre- and postmenopausal women, but postmenopausal women experience superior metabolic risk factor improvements and preserve lean body mass more effectively.

For postmenopausal women, a structured weight loss program using meal replacements and supervised aerobic exercise is highly effective. While total weight loss may be similar to younger women, the metabolic benefits (blood pressure, cholesterol, glucose) are often greater, and muscle mass is better preserved. Focus on high-protein meal replacements and consistent aerobic activity to maximize these benefits.