Research
Mixed
Men lose more absolute weight than women using the MetaWell program, but women have a higher proportion of achieving clinically significant weight loss (>5% body weight).
Both men and women can achieve significant weight loss with this program. While men tend to lose more total kilograms, women are slightly more likely to hit the clinically significant 5% weight loss milestone. Focus on your own progress rather than comparing absolute numbers with the opposite sex.
ModerateQualifiesMEDIUM confidence
Men on average lost a mean of 5.2 kg... which was significantly more than in women, who lost a mean of 3.8 kg... However, in all tested intervals of 60 days or more, a greater proportion of women than men achieved over 5% weight loss.
Why this rating
Observational subgroup analysis; statistically significant but subject to confounding by baseline characteristics.
Source
A Digital Health Weight Loss Program in 250,000 Individuals
Conor Senecal et al. · Journal of Obesity · 2020
DOI 10.1155/2020/9497164
cohort · n=251718Cited 19×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- A hybrid digital health weight loss program combining a mobile application, wireless scale, and meal replacement biscuits achieves clinically significant short- and midterm weight loss (average 5.4 kg at 120 days) without face-to-face interaction.Moderate
- Higher frequency of self-weighing via the mobile application is associated with greater weight loss in users of the MetaWell program.Moderate
Related findings · Mixed
- Bariatric surgery (VSG and RYGB) is the most effective and sustainable treatment for obesity, producing marked and sustained weight loss that non-surgical interventions cannot match.Strong
- Severely protein-deficient diets (2–3% energy) induce lean body mass loss and metabolic imbalance, whereas adequate protein intake (0.66 g/kg/d minimum) is a prerequisite for maintaining muscle, bone, and physiological function.Strong
- For patients with Class III obesity (BMI >39.9 kg/m2), metabolic bariatric surgery (MBS) is significantly more effective than any currently approved medication, with BilioPancreatic Diversion (BPD) showing the highest estimated weight loss.Strong
This is one finding among thousands. Every one is graded and traced to its source, so you can see what the evidence actually supports. Browse the research →