Research

Energy balance

A remote digital health intervention combining mobile applications, wireless scales, and low-calorie meal replacement biscuits produces clinically significant weight loss (mean 14 kg, 13% total body weight loss) in severely obese individuals (BMI ≥35 kg/m2) over 120 days.

If you have severe obesity (BMI ≥35), a structured digital program using meal replacement biscuits and daily self-weighing can lead to significant weight loss (around 13% of body weight over 4 months). The key is consistency: weigh yourself daily using a connected scale and follow the prescribed meal plan. This approach is designed to be accessible and scalable, offering a viable alternative to more invasive or expensive treatments for those who can adhere to the protocol.

ModerateSupportsMEDIUM confidence
In a large cohort of individuals with class II or III obesity, a remote weight-loss program combining mobile applications, daily self-weighing, and calorie restriction via meal replacement resulted in dramatic weight loss among subjects who were active users when evaluated through a retrospective observational analysis.
Conor Senecal et al. · Digital Health · 2020

Why this rating

Large sample size (N=8275) but retrospective observational design with no control group.

Source

A digital health weight-loss intervention in severe obesity

Conor Senecal et al. · Digital Health · 2020

DOI 10.1177/2055207620910279

cohort · n=8275Cited 17×
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DOI resolved against Crossref · corpus check 2026-06-10

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