Research
Mixed
Bariatric surgery (Roux-en-Y gastric bypass or sleeve gastrectomy) produces comparable long-term weight loss and metabolic improvements in patients with metabolic syndrome compared to those without it.
If you have severe obesity and metabolic syndrome, bariatric surgery is a highly effective option that yields long-term weight loss and metabolic improvements comparable to those without metabolic syndrome. It is currently the most effective intervention for severe cases.
ModerateSupportsMEDIUM confidence
We report that bariatric surgery results in comparable long-term weight loss in patients with or without metabolic syndrome alongside expected improvements in metabolic comorbidities.
Why this rating
Observational retrospective cohort study; lacks randomization but has long-term follow-up.
Source
Weight Loss Following Bariatric Surgery in People with or without Metabolic Syndrome: A 5-Year Observational Comparative Study
Sharanniyan Ragavan et al. · Journal of Clinical Medicine · 2024
DOI 10.3390/jcm13010256
cohort · n=333Cited 11×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
Related findings · Mixed
- Bariatric surgery (VSG and RYGB) is the most effective and sustainable treatment for obesity, producing marked and sustained weight loss that non-surgical interventions cannot match.Strong
- Severely protein-deficient diets (2–3% energy) induce lean body mass loss and metabolic imbalance, whereas adequate protein intake (0.66 g/kg/d minimum) is a prerequisite for maintaining muscle, bone, and physiological function.Strong
- For patients with Class III obesity (BMI >39.9 kg/m2), metabolic bariatric surgery (MBS) is significantly more effective than any currently approved medication, with BilioPancreatic Diversion (BPD) showing the highest estimated weight loss.Strong
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